GLUE-BOCA

Catalysis is central in many chemical processes. For example, adhesives are reticulated and polymerized using catalysts without which no reactive bonding could occur. The use of boron derivatives has the potential to replace the current tin and antimony derivatives currently used in many sealants. Unlike boronic acids, borinic acids and their derivatives are understudied species, mostly due to their tedious preparation. They display however intriguing properties and have the potential of being versatile catalysts and ligands.The aim of this project is to provide a comprehensive study of borinic acids derivatives, from their biological properties to their use in catalysis, as catalysts themselves, as ligands for transition metal complexes or as additives in ion-paring catalysis.We will elaborate a new synthesis of non-symmetrical borinates, based on the combination of organometallic catalysis and controlled addition of Grignard reagents. We will evaluate their acidic properties, for the direct synthesis of esters and amides, and we will finally investigate their potential role as metal ligands.The major and central output will be related to the development of four distinct reactions using boron based catalysts with a formulation in adhesive mixtures. This major application will be done in close collaboration between academic partners and Bostik who will apply the project results at the industrial scale.