COMPASS

The rise in cardiovascular disease among cancer patients and survivors, due to treatment side effects, poses a significant challenge to patient outcomes and healthcare systems. Managing cardiotoxicity is difficult due to its delayed onset and lack of reliable biomarkers, often requiring dose reduction or discontinuation of cancer treatment, which may compromise its effectiveness. The COMPASS project aims to optimize cardiovascular health for cancer patients and survivors through a comprehensive, patient-centered clinical pathway over five years. It will advance cardio-oncology research by creating an international network and developing tools for better disease prediction, prevention, diagnosis, and management. The project focuses on integrating cardio-oncology care pathways, optimizing diagnostic biomarkers, and utilizing AI-supported imaging and wearable technologies for early detection and personalized treatment, while promoting sustainable healthcare delivery and reducing environmental impact. COMPASS methodology includes three pillars: (i) Discovery of Novel Biomarkers and Parameters, (ii) AI Prediction Models and Clinical Decision Support System, and (iii) Improving Care Delivery and Patient Engagement. Activities across the program include Health Economics, Communication, Dissemination, Exploitation and Sustainability, and Ethics and Regulatory Aspects. This public private partnership of 51 academic and industrial partners will collaborate to translate scientific advancements into clinical applications, apply novel AI approaches, ensuring solutions are effective, meet patient needs, and align with European health policies and regulations. Key stakeholders include clinicians, nurses, patients, payers, regulators, and industry actors. COMPASS aims to advance cardio-oncology research, reduce healthcare costs, and improve patient well-being through innovative tools, collaborative networks, and policy support. Ultimately, it aims to improve patient outcomes for both cancer and heart health.