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Fully integrated chip for PET-tracer synthesis
FunderNetherlands Organisation for Scientific Research (NWO)
DurationFrom 01 Sep 2025
Funded underOpen technologieprogramma OTP 2024 2024-7
Project code22156
Identifiers
Description
Positron Emission Tomography (PET) is a medical imaging method to measure (patho)physiological processes in patients non-invasively. Clinical applications include cancer, neurology, cardiology, and inflammation/infection monitoring. PET relies on short-lived radiopharmaceuticals labelled with 18F. Current production methods are inefficient, leading to incomplete reactions and wasted materials. Our research focuses on developing a fully integrated microfluidic chip for efficient PET-radiopharmaceutical production. This chip can produce PET tracers faster, with higher yields, lower reagent consumption, and faster purification. The goal is a fully automated procedure suitable for commercialization, enabling faster and more accurate diagnoses and treatments for patients worldwide.
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Positron Emission Tomography (PET) is a medical imaging method to measure (patho)physiological processes in patients non-invasively. Clinical applications include cancer, neurology, cardiology, and inflammation/infection monitoring. PET relies on short-lived radiopharmaceuticals labelled with 18F. Current production methods are inefficient, leading to incomplete reactions and wasted materials. Our research focuses on developing a fully integrated microfluidic chip for efficient PET-radiopharmaceutical production. This chip can produce PET tracers faster, with higher yields, lower reagent consumption, and faster purification. The goal is a fully automated procedure suitable for commercialization, enabling faster and more accurate diagnoses and treatments for patients worldwide.
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