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Completed
ENRICHING TRAILS (TRacking Adolescents Individual Lives Study)
FunderNetherlands Organisation for Scientific Research (NWO)
Duration01 Jan 2005 - 13 Oct 2011
Project code175.010.2003.005
Open Access mandatePublications: NoResearch data: No
Identifiers
Project timeline100%
Description
Introduction - Mental disorders in adulthood account for a fifth of the total burden of ill-health in the Western world. Most chronic and recurrent adult psychopathology has antecedents in adolescence, a period where interaction between the individual and the environment is intense and developmental pathways are set in motion or become entrenched. How adolescence is negotiated has important consequences for adult life. The 1-year prevalence of mental disorders in the 3 million Dutch adolescents and young adults increases from about 10% at age 10-12, to circa 25% at age 23-25. Nearly half of those suffer from significant impairments. Scientific progress in understanding mental health, adjustment and social development hinges on good theories with high predictive power and high-quality data covering the life course into adulthood. The TRAILS consortium wants to establish such a comprehensive database. The TRAILS-consortium has secured funding for biennial assessments of a large cohort of children for the forthcoming ten years, hereby ensuring the creation of the first large-scale long-lasting longitudinal study from prepuberty into young adulthood in the Netherlands, in which a broad range of environmental factors, individual characteristics, and multiple aspects of health, adjustment and social development are assessed. The baseline assessment was completed end 2002. The present proposal is meant to enrich the TRAILS database by making it genetically informative, by adding online assessments to capture developmental trajectories and mechanisms in a more fine-tuned way, and by adding additional biological data. These additions will - at relatively low extra casts - create an intemationally unique and very powerful database, that will enable Dutch researchers to participate at the highest scientific international level, hereby not only serving those within the consortium, but also other interested research groups. The consortium consists of 31 senior investigators from a variety of scientific institutions and disciplinary backgrounds. They share a fascination for mental health and social development. The consortium integrates expertise at different levels of organization, ranging from the molecular to the community level, and has a strong track record in longitudinal cohort research.
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Introduction - Mental disorders in adulthood account for a fifth of the total burden of ill-health in the Western world. Most chronic and recurrent adult psychopathology has antecedents in adolescence, a period where interaction between the individual and the environment is intense and developmental pathways are set in motion or become entrenched. How adolescence is negotiated has important consequences for adult life. The 1-year prevalence of mental disorders in the 3 million Dutch adolescents and young adults increases from about 10% at age 10-12, to circa 25% at age 23-25. Nearly half of those suffer from significant impairments. Scientific progress in understanding mental health, adjustment and social development hinges on good theories with high predictive power and high-quality data covering the life course into adulthood. The TRAILS consortium wants to establish such a comprehensive database. The TRAILS-consortium has secured funding for biennial assessments of a large cohort of children for the forthcoming ten years, hereby ensuring the creation of the first large-scale long-lasting longitudinal study from prepuberty into young adulthood in the Netherlands, in which a broad range of environmental factors, individual characteristics, and multiple aspects of health, adjustment and social development are assessed. The baseline assessment was completed end 2002. The present proposal is meant to enrich the TRAILS database by making it genetically informative, by adding online assessments to capture developmental trajectories and mechanisms in a more fine-tuned way, and by adding additional biological data. These additions will - at relatively low extra casts - create an intemationally unique and very powerful database, that will enable Dutch researchers to participate at the highest scientific international level, hereby not only serving those within the consortium, but also other interested research groups. The consortium consists of 31 senior investigators from a variety of scientific institutions and disciplinary backgrounds. They share a fascination for mental health and social development. The consortium integrates expertise at different levels of organization, ranging from the molecular to the community level, and has a strong track record in longitudinal cohort research.
