Subtyping of aggression and prediction of responsivity to aggression-replacement therapy, pharmacological therapy or combined therapy in adult forensic psychiatric patients and adolescents with conduct disorder

This study examines the the additional value of neurobiological (stress measures), cognitive (executive functioning)and clinical (reactive versus instrumental aggression) subtyping of aggression in predicting the outcome of two established treatments for pathological aggression. These are aggression replacement therapy and treatment with a new generation antipsychotic. The resarch project will include adolescents (12-21 years old) with conduct disorder